1,183 research outputs found

    Spray automated balancing of rotors: Methods and materials

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    The work described consists of two parts. In the first part, a survey is performed to assess the state of the art in rotor balancing technology as it applies to Army gas turbine engines and associated power transmission hardware. The second part evaluates thermal spray processes for balancing weight addition in an automated balancing procedure. The industry survey reveals that: (1) computerized balancing equipment is valuable to reduce errors, improve balance quality, and provide documentation; (2) slow-speed balancing is used exclusively, with no forseeable need for production high-speed balancing; (3) automated procedures are desired; and (4) thermal spray balancing is viewed with cautious optimism whereas laser balancing is viewed with concern for flight propulsion hardware. The FARE method (Fuel/Air Repetitive Explosion) was selected for experimental evaluation of bond strength and fatigue strength. Material combinations tested were tungsten carbide on stainless steel (17-4), Inconel 718 on Inconel 718, and Triballoy 800 on Inconel 718. Bond strengths were entirely adequate for use in balancing. Material combinations have been identified for use in hot and cold sections of an engine, with fatigue strengths equivalent to those for hand-ground materials

    Transcript profiling during preimplantation mouse development

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    AbstractStudies using low-resolution methods to assess gene expression during preimplantation mouse development indicate that changes in gene expression either precede or occur concomitantly with the major morphological transitions, that is, conversion of the oocyte to totipotent 2-cell blastomeres, compaction, and blastocyst formation. Using microarrays, we characterized global changes in gene expression and used Expression Analysis Systematic Explorer (EASE) to identify biological and molecular processes that accompany and likely underlie these transitions. The analysis confirmed previously described processes or events, but more important, EASE revealed new insights. Response to DNA damage and DNA repair genes are overrepresented in the oocyte compared to 1-cell through blastocyst stages and may reflect the oocyte's response to selective pressures to insure genomic integrity; fertilization results in changes in the transcript profile in the 1-cell embryo that are far greater than previously recognized; and genome activation during 2-cell stage may not be as global and promiscuous as previously proposed, but rather far more selective, with genes involved in transcription and RNA processing being preferentially expressed. These results validate this hypothesis-generating approach by identifying genes involved in critical biological processes that can be the subject of a more traditional hypothesis-driven approach

    Rotating Rayleigh-Taylor instability

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    The effect of rotation upon the classical Rayleigh-Taylor instability is considered. We consider a two-layer system with an axis of rotation that is perpendicular to the interface between the layers. In general we find that a wave mode’s growth rate may be reduced by rotation. We further show that in some cases, unstable axisymmetric wave modes may be stabilized by rotating the system above a critical rotation rate associated with the mode’s wavelength, the Atwood number and the flow’s aspect ratio

    Guiding the management of an agricultural pest: Indexing abundance of California meadow voles in artichoke fields

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    Nearly 100% of U.S. artichoke production comes from California and is concentrated in Monterey County. California meadow voles are damaging rodent pests that can threaten the profitability of growing artichokes. A practical population monitoring method can be invaluable to integrated pest management programs for guiding when and where control is needed and assessing control efficacy. The standard method for indexing vole populations in artichoke fields has been based on observing chewing on artichoke bracts placed throughout the field. Because toxicants are delivered on artichoke bracts, bias for population indexing is potentially introduced. We therefore compared artichoke bracts to nontoxic grain-based wax bait blocks as an alternative chewing medium for eliciting chewing observations for indexing abundance. We also compared the use of binary (presence-absence) observations of chewing to continuous measures (percent chewed). We considered the effect of three sizes of observation grids (4 x 4, 5 x 5, 6 x 6) for indexing.We conducted intensive trapping to determine number of voles known to be alive (KTBA) at each site as a basis for assessing which of the 12 indexing approaches (2 chewing mediums, 2 measurement types, 3 grid sizes) best tracked population abundance. The percent chewed on artichoke bracts for all grid sizes only marginally correlated with KTBA (~0.5), whereas percent chewed on bait blocks correlated very well with KTBA for all grid sizes (~0.9). Reducing continuous data to binary observations produced indices only weakly or negatively correlated with KTBA. Available resources would probably determine whether smaller grid sizes would be used for obtaining chewing observations

    Guiding the management of an agricultural pest: Indexing abundance of California meadow voles in artichoke fields

    Get PDF
    Nearly 100% of U.S. artichoke production comes from California and is concentrated in Monterey County. California meadow voles are damaging rodent pests that can threaten the profitability of growing artichokes. A practical population monitoring method can be invaluable to integrated pest management programs for guiding when and where control is needed and assessing control efficacy. The standard method for indexing vole populations in artichoke fields has been based on observing chewing on artichoke bracts placed throughout the field. Because toxicants are delivered on artichoke bracts, bias for population indexing is potentially introduced. We therefore compared artichoke bracts to nontoxic grain-based wax bait blocks as an alternative chewing medium for eliciting chewing observations for indexing abundance. We also compared the use of binary (presence-absence) observations of chewing to continuous measures (percent chewed). We considered the effect of three sizes of observation grids (4 x 4, 5 x 5, 6 x 6) for indexing.We conducted intensive trapping to determine number of voles known to be alive (KTBA) at each site as a basis for assessing which of the 12 indexing approaches (2 chewing mediums, 2 measurement types, 3 grid sizes) best tracked population abundance. The percent chewed on artichoke bracts for all grid sizes only marginally correlated with KTBA (~0.5), whereas percent chewed on bait blocks correlated very well with KTBA for all grid sizes (~0.9). Reducing continuous data to binary observations produced indices only weakly or negatively correlated with KTBA. Available resources would probably determine whether smaller grid sizes would be used for obtaining chewing observations

    Measuring Fundamental Galactic Parameters with Stellar Tidal Streams and SIM PlanetQuest

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    Extended halo tidal streams from disrupting Milky Way satellites offer new opportunities for gauging fundamental Galactic parameters without challenging observations of the Galactic center. In the roughly spherical Galactic potential tidal debris from a satellite system is largely confined to a single plane containing the Galactic center, so accurate distances to stars in the tidal stream can be used to gauge the Galactic center distance, R_0, given reasonable projection of the stream orbital pole on the X_GC axis. Alternatively, a tidal stream with orbital pole near the Y_GC axis, like the Sagittarius stream, can be used to derive the speed of the Local Standard of Rest (\Theta_LSR). Modest improvements in current astrometric catalogues might allow this measurement to be made, but NASA's Space Interferometry Mission (SIM PlanetQuest) can definitively obtain both R_0 and \Theta_LSR using tidal streams.Comment: 8 pages, 4 figures, accepted for publication in ApJ Letters (minor text revisions). Version with high resolution figures available at http://www.astro.caltech.edu/~drlaw/Papers/GalaxyParameters.pd

    Efficacy of Rodenticides for Roof Rat and Deer Mouse Control in Orchards

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    Roof rats and deer mice are occasional pests of orchard crops throughout the world. The application of rodenticides is an effective and practical method for controlling rodent pests and reducing damage. However, a paucity of information exists on the efficacy of rodenticides in orchards for these pest species. To address this gap in knowledge, we first developed an index to measure rodent activity in order to monitor efficacy of rodenticides. We then used this index to test the efficacy of 3 first-generation anticoagulant rodenticide baits to determine their utility for controlling roof rats and deer mice in agricultural orchards. Of the baits tested, the 0.005% diphacinone grain bait was the most effective option for controlling both roof rats and deer mice (average efficacy = 90% and 99%, respectively). The use of elevated bait stations proved effective at providing bait to target species and should substantially limit non-target access to rodenticides

    Factors influencing treatment selection and thirty-day mortality following chemotherapy for people with small cell lung cancer: an analysis of national audit data

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    Background Thirty-day mortality after treatment for lung cancer is a measure of unsuccessful outcome and where treatment should have been avoided. Guidelines recommend offering chemotherapy to individuals with small cell lung cancer (SCLC) who have poorer performance status (PS) because of its high initial response rate. However, this comes with an increased risk of toxicity and early death. We quantified real-world 30-day mortality in SCLC following chemotherapy, established the factors associated with this and compared these to the factors that influence receipt of chemotherapy. Methods We used linked national English datasets to define the factors associated with both receiving chemotherapy and 30-day mortality following chemotherapy. Results We identified 3,715 people diagnosed with SCLC, of which 2,235 (60.2%) received chemotherapy. There were 174 (7.8%) deaths within 30 days of chemotherapy. The adjusted odds of receiving chemotherapy decreased with older age, worsening PS and increasing comorbidities. Thirty-day mortality was independently associated with poor PS (PS 2 vs PS 0 adjusted OR 3.75 95% CI 1.71-8.25) and stage (extensive vs limited adjusted OR 1.68 95% CI 1.03-2.74) but in contrast was not associated with increasing age. Both chemotherapy administration and 30-day mortality varied by hospital network.Conclusions To reduce variation in chemotherapy administration predictors of 30-day mortality could be used as an adjunct to improve sub-optimal patient selection. We have quantified 30-day mortality risk by the two independently associated factors, PS and stage, so that patients and clinicians can make better informed decisions about the potential risk of early death following chemotherapy

    Replication of the Apparent Excess Heat Effect in a Light Water-Potassium Carbonate-Nickel Electrolytic Cell

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    Replication of experiments claiming to demonstrate excess heat production in light water-Ni-K2CO3 electrolytic cells was found to produce an apparent excess heat of 11 W maximum, for 60 W electrical power into the cell. Power gains range from 1.06 to 1.68. The cell was operated at four different dc current levels plus one pulsed current run at 1 Hz, 10% duty cycle. The 28 liter cell used in these verification tests was on loan from a private corporation whose own tests with similar cells are documented to produce 50 W steady excess heat for a continuous period exceeding hundreds of days. The apparent excess heat can not be readily explained either in terms of nonlinearity of the cell's thermal conductance at a low temperature differential or by thermoelectric heat pumping. However, the present data do admit efficient recombination of dissolved hydrogen-oxygen as an ordinary explanation. Calorimetry methods and heat balance calculations for the verification tests are described. Considering the large magnitude of benefit if this effect is found to be a genuine new energy source, a more thorough investigation of evolved heat in the nickel-hydrogen system in both electrolytic and gaseous loading cells remains warranted
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